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4-Fluoro-N-Acetylglucosamine

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SKU: 8bc9c698c15a Categories: , ,

Product #: MS250000

4-Fluoro-N-Acetylglucosamine

Product Details

Other Names 4-F-GlcNAc, 2-Acetamido-2,4-dideoxy-4-fluoro-D-glucopyranose (mixed anomers)
CAS # 115973-75-6
Formula C8H14FNO5
Molecular Weight 223.2
Purity >95% (NMR)
Description Fluorinated glucosamine has been shown to block the synthesis of key carbohydrate structures linked to cancer progression via interference with UDP-GlcNAc synthesis. The anomerically racemic 4-F-GlcNAc is an inhibitor of hepatic glycosaminoglycan biosynthesis and used as a probe for the study of protein-carbohydrate interactions.
Keywords 4-Fluoro-N-Acetylglucosamine, N-Acetylglucosamine, GlcNAc, O-GlcNAcase Inhibitor, Monosaccharide, Fluorosaccharide, 4-F-GlcNAc, 2-Acetamido-2,4-dideoxy-4-fluoro-D-glucopyranose (mixed anomers), C8H14FNO5
References S.R. Barthel et al., The Journal of Biological Chemistry 2011, 286, 21717–21731.
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