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0.5mg$375.00In Stock
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1mg$600.00In Stock
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RPB1 CTD(1615-1621-Lys)-GlcNAc(1619)

$375.00 – $600.00

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SKU: 60dae70463f9 Categories: ,

Product #: GP200000

RPB1 CTD(1615-1621-Lys)-GlcNAc(1619)

Product Details

Sequence YSPTS*PSK-NH2;
Tyr-Ser-Pro-Thr-Ser*-Pro-Ser-Lys-NH2;
where S* = Ser* = GlcNAcĪ²-O-Ser
Other Names Synthetic RPB1 at C-terminal domain(CTD) glycopeptide
UniProt ID P24928
Formula C46H73N11O18
Molecular Weight 1068.1
Purity >90% (HPLC)
Description DNA-directed RNA polymerase II (Pol II) subunit RPB1 (UniProt ID P24928) contains a Carboxy Terminal Domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity. The CTD Nonconsensus Repeat, Tyr-Ser-Pro-Thr-Ser-Pro-Ser, is heavily modified by phosphorylation, glycosylation and proline isomerization. The CTD acts as a tether to bring into close proximity the machinery necessary to synthesize and process Pol II transcripts.
Keywords RPB1 CTD(1615-1621-Lys)-GlcNAc(1619), N-Acetyl-D-Glucosamine, O-Linked, Mono-Glycosylated, L-Serine, C-Terminus-Amide, GlcNAc-Glycopeptide, Formerly GP221000, Synthetic RPB1 at C-terminal domain(CTD) glycopeptide, C46H73N11O18
Shipping Requirement Dry Ice
Safety Data Sheets Email info@sussex-research.com