Pack Size Price (USD) Availability Quantity
1mg$475.00In Stock
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2mg$750.00In Stock
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5mg$1,400.00In Stock
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10mg$2,250.00In Stock
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TF Antigen: Ac-Thr(α-Galβ(1-3)GalNAc)-OCH3

$475.00 – $2,250.00

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SKU: 618adbfe8271 Categories: ,

Product #: GA134000

TF Antigen: Ac-Thr(α-Galβ(1-3)GalNAc)-OCH3

Product Details

Other Names TF Antigen (Threonine, NHAc, Methyl Ester), T Antigen (Threonine, blocked amino acid), TF Epitope (Threonine), T Antigen (Threonine), Galβ(1-3)GalNAc-α-1-O-Threonine (blocked amino acid), Thomsen–Friedenreich Antigen (blocked amino acid)
Formula C21H36N2O14
Molecular Weight 540.52
Purity >95% (HPLC)
Description Tumor-Associated Carbohydrate Antigen (TACA). TF is a truncated O-glycosylated core determinant (Core 1) with structure: Galβ1-3GalNAcα-O-Ser/Thr. In normal Mamalian cells, the TF determinant is masked by larger glycan residues. Once unmasked, TF serves as an important recognition element, mediating several cell-cell interactions. As such, TF is implicated in tumour cell organotropic metastasis. Targeting immune responses to truncated variants of O-glycan chains expressed by tumour cells represents a promising approach for the development of antigen-specific therapeutic vaccines against cancers, and accumulated evidence has rendered TF a potential target for cancer immunotherapy.
Keywords TF Antigen: Ac-Thr(alpha-Galbeta(1-3)GalNAc)-OCH3, N-Acetyl-D-Galactosamine, O-Link, Disaccharide, Threonine, Blocked, Amino Acid, Ac, TF Antigen (Threonine, NHAc, Methyl Ester), T Antigen (Threonine, blocked amino acid), TF Epitope (Threonine), T Antigen (Threonine), Galbeta(1-3)GalNAc-alpha-1-O-Threonine (blocked amino acid), Thomsen–Friedenreich Antigen (blocked amino acid), C21H36N2O14, glycoamino acid, glycoamino acids, glyco amino acid, glycocosylated amino acids
Shipping Requirement Ambient
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