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0.5mg$750.00In Stock
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1mg$1,250.00In Stock
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Biotin-HHV1-gB(50-56)-STn(53)

$750.00 – $1,250.00

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SKU: d891a11a38af Categories: ,

Product #: GP000035

Biotin-HHV1-gB(50-56)-STn(53)

Product Details

Sequence Biotin-GPAT*PAP-NH2;
Biotin-Gly-Pro-Ala-Thr*-Pro-Ala-Pro-NH2;
where T* = Thr* = Sialyl Tn = STn = Neu5Acα2-6GalNAcα-O-Thr
Other Names HHV1P, Human Herpesvirus1(Strain P), HSV-1 gB glycopeptide (synthetic fragment of envelope glycoprotein B)
UniProt ID P08665
Formula C56H88N12O23S
Molecular Weight 1329.4
Purity >90% (HPLC)
Description Herpes simplex virus-1 (HSV-1 or HHV-1) Glycoprotein B (gB) glycopeptide fragment (50-56) is an envelope protein that is essential for viral growth. Before entering host cells, HSV-1 uses this glycopeptide ligand to bind paired immunoglobulin-like type 2 receptor α (PILRα) on immune cells. PILRα belongs to the Siglec (sialic acid-binding immunoglobulin-like lectin)-like family, members of which bind sialic acid ligands. HHV1-gB(UniProt ID P08665) synthetic glycopeptide HSV-1 gB fragment (Gly50-Pro56; UniProt position 50-56, aa length 7) from the N-terminal region of Herpes Simplex Virus type-1 glycoprotein B. O-glycosylation, Sialyl Tn (Neu5Acα2-6GalNAcα-O-Thr) at position Thr53. Biotin has been conjugated at N-terminus. The C-terminus is an amide.
Keywords Biotin-HHV1-gB(50-56)-STn(53), N-Acetyl-D-Galactosamine, O-Linked, Mono-Glycosylated, L-Threonine, C-Terminus-Amide, STn-Glycopeptide, HHV1P, Human Herpesvirus1(Strain P), HSV-1 gB glycopeptide (synthetic fragment of envelope glycoprotein B), C56H88N12O23S
References Kuroki, K. et al., Proc Natl Acad Sci. USA 2014, 111, 8877–8882.
Shipping Requirement Dry Ice
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